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Isochlorogenic acid A

Product Name
Isochlorogenic acid A
CAS No.
2450-53-5
Chemical Name
Isochlorogenic acid A
Synonyms
3,5-Dicaffeoylquinic acid;3,5-CQA;CJ 4-16-4;Isochloric acid A;Isochlorogenic acid A;3,5-Dicaffeylquinic acid;ISOCHLOROGENIC ACID A(SH);3',5'-Isochlorogenic acid A;Quinic acid 3,5-di-O-caffeate;Isochlorogenic acid A, froM Lonicera japonica
CBNumber
CB81040694
Molecular Formula
C25H24O12
Formula Weight
516.46
MOL File
2450-53-5.mol
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Isochlorogenic acid A Property

Melting point:
>175°C (dec.)
Boiling point:
826.2±65.0 °C(Predicted)
Density 
1?+-.0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Off-white to yellow/brown crystalline solid.
pka
3.54±0.50(Predicted)
color 
Off-White to Pale Yellow
Stability:
Hygroscopic
InChIKey
KRZBCHWVBQOTNZ-PSEXTPKNSA-N
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Safety

Safety Statements 
24/25
WGK Germany 
3
RTECS 
GU8403966
HS Code 
29189900
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SMB00131
Product name
3,5-Di-caffeoylquinic acid
Purity
≥95% (LC/MS-ELSD)
Packaging
1mg
Price
$306
Updated
2024/03/01
Sigma-Aldrich
Product number
PHL80426
Product name
3,5-Dicaffeoylquinic acid
Purity
phyproof Reference Substance
Packaging
10mg
Price
$777
Updated
2024/03/01
Cayman Chemical
Product number
24964
Product name
3,5-Dicaffeoylquinic Acid
Purity
≥98%
Packaging
5mg
Price
$79
Updated
2024/03/01
Cayman Chemical
Product number
24964
Product name
3,5-Dicaffeoylquinic Acid
Purity
≥98%
Packaging
10mg
Price
$141
Updated
2024/03/01
Cayman Chemical
Product number
24964
Product name
3,5-Dicaffeoylquinic Acid
Purity
≥98%
Packaging
25mg
Price
$312
Updated
2024/03/01
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Isochlorogenic acid A Chemical Properties,Usage,Production

Description

3,5-Dicaffeoylquinic acid (3,5-DCQA) is a natural phenolic compound that has been found in L. japonica, I. kaushue, and other plants. It has antioxidant, anti-inflammatory, and antiviral biological activities. 3,5-DCQA scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in a cell-free assay (IC50 = 71.8 μM) and inhibits superoxide production in human neutrophils activated by N-formyl-Met-Leu-Phe (fMLF) and cytochalasin B (IC50 = 1.92 μM). It inhibits HIV-1 integrase 3''-end processing, strand transfer, and disintegration in a cell-free assay (IC50s = 0.33, 0.34, and 0.66 μg/ml, respectively) and inhibits HIV-1-induced cytotoxicity in MT-2 cells (ED50 = 1 μg/ml). In vivo, 3,5-DCQA (25 mg/kg) protects mice from acute lung injury induced by LPS and decreases neutrophil count in bronchoalveolar lavage fluid (BALF).

Uses

Isochlorogenic Acid A is a phenolic compound shown to provide protection against oxidative stress cells. DNA protective agent.

Definition

ChEBI: 3,5-di-O-caffeoyl quinic acid is a carboxylic ester that is the diester obtained by the condensation of the hydroxy groups at positions 3 and 5 of (-)-quinic acid with the carboxy group of trans-caffeic acid. Isolated from Brazilian propolis and Suaeda glauca, it exhibits hepatoprotective and cytotoxic activities. It has a role as a metabolite, a hepatoprotective agent and an antineoplastic agent. It is a cyclitol carboxylic acid and a carboxylic ester. It is functionally related to a (-)-quinic acid and a trans-caffeic acid.

Isochlorogenic acid A Preparation Products And Raw materials

Raw materials

Preparation Products

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Isochlorogenic acid A Suppliers

China 193 Germany 2 India 1 Switzerland 1 United Kingdom 2 United States 17 Global 216
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4863
Advantage
58
AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
Fax
+1 (866) 333-9607
Email
info@adooq.com
Country
United States
ProdList
2784
Advantage
58
ALB Technology Limited
Tel
702-983-3769
Fax
702-983-3769
Email
sales@albtechnology.com
Country
United States
ProdList
2993
Advantage
55
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8449
Advantage
60
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4662
Advantage
60
Aladdin Scientific
Tel
+1-833-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57511
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354
Email
support@targetmol.com
Country
United States
ProdList
19973
Advantage
58
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View Lastest Price from Isochlorogenic acid A manufacturers

Career Henan Chemical Co
Product
Isochlorogenic acid A 2450-53-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
25kg
Release date
2019-07-12

2450-53-5, Isochlorogenic acid ARelated Search:

EPA Cryptochlorogenic acid Ethyl 2-(Chlorosulfonyl)acetate Folic acid Citric acid Stearic acid Diethyl succinosuccinate Dibutyryl adenosine cyclophosphate calcium Isochlorogenic acid C,Isochlorogenic acid C，4,5-Dicaffeoylquinic acid Isochlorogenic Acid B Taxifolin Isochlorogenic acid C (E,E)-3,5-Di-O-caffeoylquinic acid Ascoric Acid Fluorescein isothiocyanate isomer I [1S-(1alpha,3beta,4beta,5alpha)]-3-[[3-(3,4-dihydroxyphenyl)-1-oxoallyl]oxy]-1,4,5-trihydroxycyclohexanecarboxylic acid CYCLOHEPTYL ISOTHIOCYANATE Ethoxycarbonyl Isothiocyanate

  • 3,5-Dicaffeoylquinic acid
  • Isochlorogenic acid A
  • Isochlorogenic acid A，3,5-Dicaffeoylquinic acid
  • 3α,5β-Bis[[1-oxo-3-(3,4-dihydroxyphenyl)-2-propenyl]oxy]-1α,4α-dihydroxycyclohexane-1-carboxylic acid
  • 1α,4α-Dihydroxy-3β,5α-bis[3-(3,4-dihydroxyphenyl)propenoyloxy]cyclohexanecarboxylic acid
  • 1β,4β-Dihydroxy-3β,5α-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1α-cyclohexanecarboxylic acid
  • 1β,4β-Dihydroxy-3β,5α-bis[3-(3,4-dihydroxyphenyl)acryloyloxy]cyclohexane-1-carboxylic acid
  • 1β,4β-Dihydroxy-3β,5α-bis[3-(3,4-dihydroxyphenyl)propenoyloxy]cyclohexanecarboxylic acid
  • 3β,5α-Bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1β,4β-dihydroxycyclohexanecarboxylic acid
  • 3,5-Dicaffeylquinic acid
  • CJ 4-16-4
  • Quinic acid 3,5-di-O-caffeate
  • ISOCHLOROGENIC ACID A(SH)
  • Isochlorogenic acid A, froM Lonicera japonica
  • Isochlorogenic acid A, 98%, from Lonicera japonica Thunb.
  • 3,5-Di-O-caffeoylquinic acid，Isochlorogenic acid A
  • Isochlorogenic acid A, 98%, from Lonicera japonica
  • 3,5-CQA
  • Cyclohexanecarboxylic acid, 3,5-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-1,4-dihydroxy-, (1α,3R,4α,5R)-
  • 3',5'-Isochlorogenic acid A
  • (3R,5R)-3,5-Bis{[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]oxy}-1,4-dihydroxycyclohexanecarboxylic acid
  • Isochloric acid A
  • (1R,3R,4S,5R)-3,5-Bis((3-(3,4-dihydroxyphenyl)acryloyl)oxy)-1,4-dihydroxy-3-methylcyclohexane-1-carboxylic acid
  • 2450-53-5
  • The group of Chlorogenic acid
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Aromatic Phenols